Apraclonidine causes serious lethargy in infants New research suggests that an eyedrop used to diagnose a uncommon syndrome in infants could cause severe lethargy long lasting up to 10 hours and requiring hospital admission and oxygen administration. Patrick Watts and coauthors described five cases of severe drowsiness or unresponsiveness after infants under six months of age were administered 1 percent apraclonidine eyedrops medication in Australia . Related StoriesBoston Kids's and Rock Health synergy to accelerate development of pediatric health technologiesCHOP's Buerger Center for Advanced Pediatric Treatment celebrates grand openingStudy: Post medical center syndrome is significant risk factor for sufferers undergoing elective surgeryApraclonidine was developed to lessen intraocular pressure and minimize the systemic side effects associated with the use of its parent medication, clonidine.
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That’s very impressive.’ Boceprevir, a product of Merck & Co., can be an HCV protease inhibitor – a compound designed to block a function key to viral reproduction in the cell. Boceprevir targets the hepatitis C virus directly, Kwo noted, while ribavirin and peginterferon are much less specific, acting even more generally to promote your body’s virus-fighting immune system. The best outcomes were reported for the 103 sufferers who had been treated for a month with the standard two drug regiment, accompanied by 44 weeks of the three-drug regimen including boceprevir: 75 % of the patients tested bad for proof the virus half a year after the end of treatment. Results for the various other treatment hands had been: 67 % of those who received the three drug program for 48 weeks with no lead-in treatment tested negative for the virus .